Analysis of pharmacodynamic markers using microdialysis

Microdialysis enables evaluation of biological changes
that happen just there at the moment.

Pharmacodynamic(PD) markers are critically important to understand efficacy and mechanism of action. Samples (ex. brain interstitial fluid) can be serially collected from various tissues, such as brain, tumor, and etc, for analysis of PD markers by using microdialysis. In addition, Axcelead offers analysis of various molecules including monoamines, amino acids peptides, and proteins (ex. neurotransmitters, hormones, pathology-related proteins, inflammatory cytokines) .

Targeting a specific region of tissues of customer’s interest

More physiologically relevant evaluation by simultaneous analysis of PD marker and physiological changes in the same animal